Tian-shui Niu

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The majority of renal cell carcinomas (RCCs) are characterized by loss of function of the tumor suppressor gene von Hippel Lindau (VHL), which acts as ubiquitin ligase for hypoxia-inducible factor-1α (HIF-1α). In the absence of VHL, HIF-1α protein becomes stabilized and contributes to tumorigenesis. Recent data demonstrate the antitumor efficacy of VHL(More)
The authors retract this publication due to concerns about the cell lines employed in the study. One part of the study involves an assessment of the effects of NDRG2 on the expression of pVHL, HIF-1a and VEGF in 786O cells. After the publication of the article, a reader raised concerns that the human renal cancer cell lines 786-O and A498 used in the study(More)
Nano materials is a new type of drug carriers with very promising application. In recent years, great progress was achieved in making drugs own the characteristics of targeted and controlled release via nanotechnologies. This paper addressed the capability of nano drugs on targeting to cells, penetrating through epicyte, controlled release and the security(More)
OBJECTIVE To study the alkaloid component of Corydalis adunca Maxim. METHODS The constituents were isolated by chromatographic methods, their structures were elucidated by spectroscopic evidences. RESULTS Three compounds were purified and their structures were identified, they were identified as dorydaline (I), dehydrocorydaline (II),(More)
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