Tiago de Oliveira

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The cytochrome c nitrite reductase (cNiR) isolated from Desulfovibrio vulgaris Hildenborough is a membrane-bound complex formed of NrfA and NrfH subunits. The catalytic subunit NrfA is a soluble pentahaem cytochrome c that forms a physiological dimer of about 120 kDa. The electron-donor subunit NrfH is a membrane-anchored tetrahaem cytochrome c of about 18(More)
Cell motility is controlled by the dynamic cytoskeleton and its related proteins, such as members of the ezrin/radixin/moesin (ERM) family, which act as signalling molecules inducing cytoskeleton remodelling. Although ERM proteins have been identified as important factors in various malignancies, functional redundancy between these proteins has hindered the(More)
Dysregulation of tumor suppressor protein E-cadherin is an early molecular event in cancer. O-mannosylation profile of E-cadherin is a newly-described post-translational modification crucial for its adhesive functions in homeostasis. However, the role of O-mannosyl glycans in E-cadherin-mediated cell adhesion in cancer and their interplay with N-glycans(More)
In this paper a new general recurrent state-space Neuro-Fuzzy model structure based on the combination of a modified Jordan network and an Adaptive Neuro-Fuzzy Inference System is proposed. The Neural-Fuzzy System's online training is carried out based on a Constrained Unscented Kalman Filter, where weights, membership functions and consequents are(More)
Chagas disease is a very important neglected disease and millions of people live in endemic areas at the risk of acquiring the infection. Due to scarce and ineffective current chemotherapy, the introduction of new drugs on therapeutics is highly necessary. Bioisoster hybrids derivatives were previously designed, synthesized, and assayed in terms of(More)
To Professor João Tiago Mexia, a token of friendship. Abstract In this article, we begin with an asymptotic comparison at optimal levels of the so-called " maximum likelihood " (ML) extreme value index estimator, based on the excesses over a high random threshold , denoted PORT-ML, with PORT standing for peaks over random thresholds, with a similar ML(More)
Autonomous Underwater Vehicles and Remotely Operated Vehicles are useful in industries such as offshore Oil and Gas, deep sea mining, and aquaculture, where inspection missions are frequent. While underwater communications are mainly done using acoustic links, retrieving data from these devices to shore is still an open issue, especially when we consider(More)