BACKGROUND AND OBJECTIVES Complete blanching of port wine stain (PWS) birthmarks after laser therapy is rarely achieved for most patients. We postulate that the low therapeutic efficacy or treatment failure is caused by regeneration and revascularization of photocoagulated blood vessels due to angiogenesis associated with the skin's normal wound healing… (More)
GHK Holdings and its subsidiaries were acquired by ICF International.
Introduction Akt/PKB is a serine/threonine protein kinase that is activated by various growth factors and cytokines, including many angiogenic factors such as VEGF (1, 2). Akt signaling in endothelial cells regulates multiple critical steps in angiogenesis through its downstream effectors, mTOR and eNOS among others. We applied MRI to investigate vascular… (More)