Thuttagunta Manikya Sastry

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A simple and sensitive spectrophotometric method has been developed for the assay of lercanidipine hydrochloride (LER) in bulk and in formulations. The method is based on the formation of coloured species between the drug and 1,2-naphthaquinone-4-sulphonic acid sodium salt (NQS) by means of nucleophilic substitution reaction. Absorbance was measured at(More)
Two simple and sensitive spectrophotometric methods have been developed for the assay of bioactive compound: lercanidipine hydrochloride (LER) in bulk and in formulations. The methods A and B are based on the formation of coloured species between the drug and brucine in the presence of sodium periodate in acid medium, or 2, 6-dichloroquinone-4-chlorimide(More)
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