Learn More
Our study documents the clinical and electrographic findings in 42 patients with medically refractory occipital lobe epilepsy, who underwent surgery at the Montreal Neurological Institute between 1930 and 1991, and the evolving manner in which those patients were studied by successive generations of investigators. In more than two-thirds of the patients the(More)
Hemispherectomy is effective in arresting seizures associated with maximal or near maximal hemiparesis. This procedure, however, carries an unacceptable 33% risk of late complications due to cerebral hemosiderosis. Anatomically partial but functionally complete hemispherectomy was devised to avoid these complications. The frontal or occipital lobes, or(More)
We compared 100 patients with temporal lobe epilepsy, who exhibited the running down phenomenon following temporal resections, with two groups of patients: 100 patients who became seizure-free, and 100 patients who continued to have frequent seizures following temporal resection. We found a significant correlation between prognosis and the size of the(More)
Between 1929 and 1980, 284 patients with refractory nontumoral frontal lobe epilepsy (FLE) underwent operation at the Montreal Neurological Institute (MNI). We studied 39 patients (14%) who required reoperation. Mean age at the time of first operation was 18 years and at reoperation was 22 years. Clinical manifestations were similar to those of patients(More)
Chronic encephalitis and epilepsy (Rasmussen's encephalitis) is a rare progressive disorder of uncertain etiology that usually occurs in children, producing focal epilepsy, hemiparesis, and intellectual deterioration. We identified 13 patients in whom seizures developed in adolescence or adulthood with a pathologic picture of chronic encephalitis. The(More)
Poor localization of the interictal epileptic abnormality and the rather unreliable EEG localization of ictal onsets in patients with frontal lobe epilepsy may be due to some of the following factors: (1) high risk of EEG sampling error, (2) early seizure spread within and outside the frontal lobe, (3) widespread distribution of the epileptogenic brain(More)
BACKGROUND Seizures in patients with tuberous sclerosis complex (TSC) are often intractable to antiepileptic medications and searching investigation may provide evidence that surgical treatment can be considered. OBJECTIVE To review the results of investigation and surgical therapy, a treatment modality not generally considered in patients with medically(More)
Etiologic, pathologic, and clinical features of possible prognostic significance were studied in 118 children who underwent frontal or temporal lobe epilepsy surgery at the Montreal Neurological Institute (MNI) between 1940 and 1980 (excluding tumor cases). Mean age of seizure onset was 5.1 years (range 0-12 years), mean age at operation was 11.7 years(More)
The ictal clinical manifestations of 40 patients with frontal lobe epilepsy who became and remained seizure free after selective removal of the parasagittal or anterolaterodorsal convexities were studied. Seizures arising from the parasagittal region were characterized by a high incidence of somatosensory auras (60%) and by tonic and/or clonic motor(More)
BACKGROUND The prognostic significance of epileptiform activity (EA) recorded intraoperatively at electrocorticography (ECOG) in patients with lesion-related frontal lobe epilepsy (FLE) is unknown. METHODS The results of ECOG performed in 22 patients with intractable FLE and a circumscribed frontal lobe structural lesion were compared with postoperative(More)