Thomas Wunderle

Learn More
Long-range horizontal connections are thought to modulate the responsiveness of neurons by supplying contextual information. A special type of long-range connections are interhemispheric projections, linking the 2 cerebral hemispheres. To investigate the action of those projections in a causal approach, we recorded in cat primary visual cortex while(More)
In neuroscience, data are typically generated from neural network activity. The resulting time series represent measurements from spatially distributed subsystems with complex interactions, weakly coupled to a high-dimensional global system. We present a statistical framework to estimate the direction of information flow and its delay in measurements from(More)
Even though the visual cortex is one of the most studied brain areas, the neuronal code in this area is still not fully understood. In the literature, two codes are commonly hypothesized, namely stimulus and predictive (error) codes. Here, we examined whether and how these two codes can coexist in a neuron. To this end, we assumed that neurons could predict(More)
Neurons in the cerebral cortex are constantly integrating different types of inputs. Dependent on their origin, these inputs can be modulatory in many ways and, for example, change the neuron's responsiveness, sensitivity, or selectivity. To investigate the modulatory role of lateral input from the same level of cortical hierarchy, we recorded in the(More)
It is generally thought that callosal connections (CCs) in primary visual cortices serve to unify the visual scenery parted in two at the vertical midline (VM). Here, we present evidence that this applies also to visual features that do not cross yet but might cross the VM in the future. During reversible deactivation of the contralateral visual cortex in(More)
Cognition requires the dynamic modulation of effective connectivity, i.e., the modulation of the postsynaptic neuronal response to a given input. If postsynaptic neurons are rhythmically active, this might entail rhythmic gain modulation, such that inputs synchronized to phases of high gain benefit from enhanced effective connectivity. We show that visually(More)
Neuronal activity generates ionic flows and thereby both magnetic fields and electric potential differences, i.e., voltages. Voltage measurements are widely used but suffer from isolating and smearing properties of tissue between source and sensor, are blind to ionic flow direction, and reflect the difference between two electrodes, complicating(More)
Ongoing brain activity exhibits patterns resembling neural ensembles co-activated by stimulation or task performance. Such patterns have been attributed to the brain's functional architecture, e.g. selective long-range connections. Here, we directly investigate the contribution of selective connections between hemispheres to spontaneous and evoked maps in(More)
  • 1