Thomas Wittenberg

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Although mammographic density is an established risk factor for breast cancer, its use is limited in clinical practice because of a lack of automated and standardized measurement methods. The aims of this study were to evaluate a variety of automated texture features in mammograms as risk factors for breast cancer and to compare them with the percentage(More)
OBJECTIVES The interpretation of endoscopic findings by gastroenterologists is still a difficult and highly subjective task. Despite important developments such as chromo-endoscopy, pit pattern analysis, fluorescence imaging as well as narrow band imaging it still requires lots of experience and training with a certain tentativeness until the final biopsy.(More)
A new high-speed system for recording, processing, and analyzing vocal fold vibrations has been developed. Results obtained with this system are discussed from the technical and the medical points of view. Laryngeal movement can be recorded with a digital high-speed camera, at a maximum speed of about 5 600 frames/s and the sequence can contain as many as 8(More)
There is growing evidence that certain breast cancer (BC) risk factors specifically increase the risk for specific molecular tumor subtypes. Different molecular subtypes of BC can partly be described by analyzing proliferation in tumors. Very few data are available regarding the association of mammographic density (MD), as a BC risk factor, with(More)
For many breast cancer (BC) risk factors, there is growing evidence concerning molecular subtypes for which the risk factor is specific. With regard to mammographic density (MD), there are inconsistent data concerning its association with estrogen receptor (ER) and progesterone receptor (PR) expression. The aim of our study was to analyze the association(More)
This paper describes the combination of the work of speech therapists and speech recognition systems. Our long term goal is to evaluate the degree of stuttering during therapy and to use the automatic analysis of stuttered speech as a screening method, e.g. the search for potential stutterers at an early age. The approach is to have a patient read a(More)
An increasing number of free software tools have been made available for the evaluation of fluorescence cell micrographs. The main users are biologists and related life scientists with no or little knowledge of image processing. In this review, we give an overview of available tools and guidelines about which tools the users should use to segment(More)
Modern techniques for medical diagnostics and therapy in keyhole surgery scenarios as well as technical inspection make use of flexible endoscopes. Their characteristic bendable image conductor consists of a very limited number of coated fibers, which leads to so-called comb structure. This effect has a negative impact on further image processing steps such(More)
The discrimination of benign and malignant types of mammographic masses is a major challenge for radiologists. The classic Eigenfaces method was recently adapted for the detection of masses in mammograms. In the work at hand we investigate if this method is also suited for the problem of distinguishing benign and malignant types of this mammographic lesion.(More)
This article shows some examples of applications of digital high-speed imaging in phoniatrics. Advantages and disadvantages of digital high-speed imaging as compared to the current world-wide standard, videostroboscopy, are discussed as well as possible future developments in this area. Parts of this paper were presented by the authors at the Pan European(More)