Learn More
Motivation: This article presents a method for assembling shotgun sequences which primarily uses high confidence regions whilst taking advantage of additional available information such as low confidence regions, quality values or repetitive region tags. Conflict situations are resolved with routines for analysing trace signals. Results: Initial tests with(More)
This paper describes data protection and data security requirements of a cross-institutional electronic patient record, and presents possible solutions for meeting these requirements. A comprehensive analysis of literature and legal documents was performed. Beside the general requirements that the EPR of a single institution must meet, specific requirements(More)
BACKGROUND Studies that use electronic health databases as research material are getting popular but the influence of a single electronic health database had not been well investigated yet. The United Kingdom's General Practice Research Database (GPRD) is one of the few electronic health databases publicly available to academic researchers. This study(More)
After reporting on characteristics, structure and contents of the specialised informatics-based curriculum for medical informatics (MI) at the University of Heidelberg/University of Applied Sciences Heilbronn, the paper describes the development during the last 5 years, and in particular a complementary health care oriented postgraduate program in 'Health(More)
BACKGROUND Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate structures nor an established universal structure encoding scheme for computational purposes. Funding for further development of the Complex Carbohydrate Structure Database (CCSD or(More)
Adverse drug events (ADEs) are a major limitation of drug safety. They are often caused by inappropriate selection of dose and the concurrent use of drugs modulating each other (drug interaction). Risk assessment and prevention strategies must therefore consider co-administered drugs, individual doses, and their timing. In a new approach we evaluated the(More)