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This communication highlights a course status of the AUTOSAR development partnership by spring 2006. A first comprehensive set of specifications has been achieved, which is referred to as Release 2.0. Major parts of this release are now available for download. The partnership applies a proof of concept approach based on prototype implementations. The(More)
BACKGROUND Increased arterial stiffness, determined invasively, has been shown to predict a higher risk of coronary atherosclerosis. However, invasive techniques are of limited value for screening and risk stratification in larger patient groups. METHODS AND RESULTS We prospectively enrolled 465 consecutive, symptomatic men undergoing coronary angiography(More)
We recently developed a novel method for assessment of arterial wave reflections (ARCSolver method): based on adopted Windkessel methods, flow curves are estimated from pressure waveforms, and wave separation analysis is performed, yielding the amplitudes of the forward and backward waves. The aim of this study was to investigate their clinical correlates(More)
/Summary The AUTomotive Open System ARchitecture (AUTOSAR) was founded as a development partnership in 2003 and produced the first set of major specifications by the end of its AUTOSAR Release 4.0 will follow by the end of 2009. With Release 2.1 and Release 3.0/3.1 the majority of partners and members started their series roll-out of AUTOSAR. When(More)
The automatic acquisition of structured object maps requires sophisticated perceptual mechanisms that enable the robot to recognize the objects that are to be stored in the robot map. This paper investigates a particular object recognition problem: the automatic detection and classi£cation of gateways in of£ce environments based on laser range data. We will(More)
The remarkable progress in characterizing the human genome sequence, exemplified by the Human Genome Project and the HapMap Consortium, has led to the perception that knowledge and the tools (e.g., microarrays) are sufficient for many if not most biomedical research efforts. A large amount of data from diverse studies proves this perception inaccurate at(More)
The prognostic value of central systolic blood pressure has been established recently. At present, its noninvasive assessment is limited by the need of dedicated equipment and trained operators. Moreover, ambulatory and home blood pressure monitoring of central pressures are not feasible. An algorithm enabling conventional automated oscillometric blood(More)
Shaders are a fundamental pattern of the modern graphics pipeline. This paper presents a syllabus for an introductory computer graphics course that emphasizes the use of programmable shaders while teaching raster-level algorithms at the same time. We describe a Java-based framework that is used for programming assignments in this course. This framework(More)
Within the last decade the quantification of pulse wave reflections mainly focused on measures of central aortic systolic pressure and its augmentation through reflections based on pulse wave analysis (PWA). A complementary approach is the wave separation analysis (WSA), which quantifies the total amount of arterial wave reflection considering both aortic(More)
Sepsis is a major cause of mortality during the neutropenic phase after intensive cytotoxic therapies for malignancies. Improved management of sepsis during neutropenia may reduce the mortality of cancer therapies. Clinical guidelines on sepsis treatment have been published by others. However, optimal management may differ between neutropenic and(More)