Ridge Energy Storage would like to acknowledge the following team members on the study. Their efforts and diligence were invaluable during all stages of the study.
Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in the pancreatic islets of insulin-resistant mouse models and type 2 diabetic human subjects.… (More)
In his writings on the milieu intérieur, Claude Bernard first hypothesized on the presence of feedback mechanisms within the cell to maintain its steady-state physiology. 1 Walter Bradford Cannon would subsequently build on this concept and coin the term homeostasis. To date, numerous counter-regulatory mechanisms have been characterized in the cell,… (More)