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Fourteen 7-alkoxy-2,2-dimethychromenes were synthetized and studied in JH competition experiments: precocenes (Ps) PI and PII, and synthetic analogs (PAs) including (i) three with both antiallatal and P-like activities: 7-ethoxy-PII (7-EPII); 7-(prop-2-ynyloxy)-2,-2-dimethylchromene (PPI); and 6-methoxy-7-(prop-2-ynyloxy)-2,2-dimethylchromene (PPIII); (ii)(More)
Precocenes (PI and PII) and 114 of their analogs (PAs) were synthetized and tested on C. remanei embryos for their precocene-like (P-like) activities resulting in unusual development at sublethal doses. The P-like activity was quantitated by plotting the probit of the percentage of the developmentally affected survivors against the (log) dose to obtain the(More)
Fourteen precocene-1 (P1) derivatives differing at C-7 were synthetized and tested for their antiallatal activities on Locusta migratoria (in vitro and in vivo) and nematocidal effects on Caenorhaditis elegans. An outstanding antiallatal effect was produced by 7-propargyloxy-P1 in vitro. It caused an elevated rate of mortality when applied in vivo to(More)
Rat liver nuclei were isolated in the presence of a nonionic detergent, and the soluble proteins were extracted from them using low-salt solution. The isolated nuclei were then embedded in a fibrin clot which was cut into 4 to 5 mm3 pieces and placed into an AMICON pressure cell in the presence and absence of the soluble nuclear proteins. When the soluble(More)
Diet containing diquat dibromide (1,000 or 2,000 ppm) caused an extension of the first-instar stadium of Neobellieria bullata (Parker); the first molt was primarily disturbed. Pupariation was delayed when early-wandering larvae had been injected with diquat dibromide (18 micrograms/larva; approximately to 150 ppm). This effect of diquat dibromide was(More)
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