Thomas T. Hewett

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This paper addresses the problem of creating a human-centered computer-based support environment to facilitate innovation and creative work. It focuses on key factors to be considered in the design and development of any such user support environment regardless of the specific domain for which it may be implemented. The paper reviews psychological(More)
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Stochastic reservoir models must honor as much input data as possible to be reliable numerical models of the reservoir under study. Traditional simulation algorithms are unable to honor either complex geological/morphological patterns or engineering data from well tests. The technique developed in this dissertation may be used to incorporate such(More)
OBJECTIVE The human bone marrow contains mesenchymal stem cells capable of differentiating along multiple mesenchymal cell lineages. Using a non-human primate model, we sought to determine whether the systemic infusion of baboon-derived mesenchymal stem cells was associated with toxicity and whether these cells were capable of homing to and persisting(More)
In a recent paper, Gould and Lewis (1983a) argued for the importance of four key principles in computer system design. These principles are: early focus on users, interactive design, empirical measurement, and iterative design. Gould and Lewis also express their belief that these principles are essential to successful design and refer to an example of their(More)
This paper addresses the problem of creating a human-centered computer-based support environment to facilitate innovation and creative work. It focuses on key factors to be considered in the design and development of any such user support environment regardless of the specific domain for which it may be implemented. The paper reviews psychological(More)
Some years ago I undertook to develop a course in Software Psychology. Originally using the model in Shneiderman's book (1980), I gradually modified the course to suit my own interests and conception of the field. Currently, the course focuses on two issues---the cognitive psychology of computer programming and the application of cognitive psychology to(More)
This is the first of two articles that report on the development, testing, and evaluation of the Individualized Instruction for Data Access System (IIDA). IlDA is an ex. ample of a class of computer systems which serve as intermediaries, enabling their users to perform a complex task on another computer, and which are coming to be known as expert systems.(More)
In the following, we describe our vision of a collaborative engineering environment, the Collaborative Design Studio, consider issues and questions relating to the effective design and evaluation of such systems, and describe proposed studies for evaluating and evolving the current environment. This work is being undertaken at the Geometric and Intelligent(More)
Quiescence has been thought to be required for the retention of the full biological potential of pluripotent hematopoietic stem cells (PHSCs). This hypothesis has been challenged recently by the observation that all murine PHSCs cycle continuously and constantly contribute to steady-state blood cell production. It was asked whether these observations could(More)