Thomas Stephan Heinrich

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PURPOSE Although cortical contrast adaptation has been extensively studied with both psychophysical and electrophysiological techniques, little is known about retinal contrast adaptation in humans. METHODS Retinal and cortical long-term contrast adaptation was assessed with simultaneous measurement of pattern electroretinogram (PERG) and cortical visual(More)
Contrast adaptation occurs in both the retina and the cortex. Defining its spatial dependence is crucial for understanding its potential roles. We thus asked to what degree contrast adaptation depends on spatial frequency, including cross-adaptation. Measuring the pattern electroretinogram (PERG) and the visual evoked potential (VEP) allowed separating(More)
OBJECTIVE Ethics training has become a core component of medical student and resident education. Curricula have been developed without the benefit of data regarding the views of physicians-in-training on the need for ethics instruction that focuses on practical issues and professional development topics. METHODS A written survey was sent to all medical(More)
Mass responses that are obtained using electrophysiological or psychophysical techniques are inadequate to characterize motion detectors at the single-unit level. Therefore, we have modelled a population of motion detectors and fitted their mass response to motion-onset EEG data. By examining a single unit of the modelled population we could assess the(More)
Previous studies of human contrast adaptation employing visually evoked potentials (VEP) have revealed contradictory results, namely, either a reduction or an enhancement in VEP amplitude. In a cross-adaptation experiment, we explored the possibility that differences in the temporal frequency of adapting and test patterns played a role. Phase-reversing(More)
Interfaces provide the structural basis for function as, for example, encountered in nature in the membrane-embedded photosystem or in technology in solar cells. Synthetic functional multilayers of molecules cooperating in a coupled manner can be fabricated on surfaces through layer-by-layer self-assembly. Ordered arrays of stimulus-responsive rotaxanes(More)
The production of high-quality self-assembled monolayers (SAMs) followed by layer-by-layer (LbL) self-assembly of macrocycles is essential for nanotechnology applications based on functional surface films. To help interpret the large amount of data generated by a standard ToF-SIMS measurement, principal component analysis (PCA) was used. For two examples,(More)
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