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BACKGROUND Acute subdural hematomas (aSDHs) are found in up to one-third of patients with severe traumatic brain injury and are associated with an unfavorable outcome in the majority of cases. Mortality ranges between 40 and 60%, but was reported to be even higher in patients undergoing oral anticoagulation therapy (OAT) at the time of injury. The objective(More)
The rigorous coupled wave analysis (RCWA) is a widely used method for simulating diffraction from periodic structures. Since its recognized formulation by Moharam [J. Opt. Soc. Am. A12, 1068 and 1077 (1995)], there still has been a discussion about convergence problems. Those problems are more or less solved for the diffraction from line gratings, but there(More)
Self-assembled, biodegradable materials that embed fragile, soluble, or insoluble compounds of therapeutic interest have potential use as drug delivery systems. The bead-forming peptide Ac-X3-gT can embed hydrophobic and hydrophilic payloads. Loaded peptide beads were internalized by human acute monocytic leukemia cell line (THP-1) macrophages, THP-1(More)
Tikhonov functionals are known to be well suited for obtaining regularized solutions of linear operator equations. We analyze two iterative methods for finding the minimizer of norm-based Tikhonov functionals in Banach spaces. One is the steepest descent method, whereby the iterations are directly carried out in the underlying space, and the other one(More)
— To meet fast changing demands on modern software architectures the ambition to shorten and improve software development processes has increased. The approach of model-driven software development focuses models as specification of software and on transformations of those models to finally get source code. The advantage of the model-driven approach still(More)
In order to increase efficiency, enterprises support their business processes by information technology (IT). The majority of business processes requires human interaction. Human interaction results in a growing complexity of the supporting IT. Model-driven approaches to software development are a promising solution to be able to cope with this complexity.(More)