Thomas S. Rector

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OBJECTIVE To examine the effects of varying diagnostic and pharmaceutical criteria on the performance of claims-based algorithms for identifying beneficiaries with hypertension, heart failure, chronic lung disease, arthritis, glaucoma, and diabetes. STUDY SETTING Secondary 1999-2000 data from two Medicare+Choice health plans. STUDY DESIGN Retrospective(More)
BACKGROUND & AIMS Colon cancers that develop after a complete colonoscopy may be the result of "failure of colonoscopy" or rapid tumor growth. Tumors that develop via the mismatch repair gene pathway demonstrate rapid tumor growth. The aim of this study was to determine if interval colon cancers were more likely than noninterval cancers to result from the(More)
BACKGROUND Anemia is known to be a prognostic marker for patients with heart failure. However, little is known about the prognostic value of changes in hemoglobin (Hgb) over time or about the causes of anemia. METHODS AND RESULTS Retrospective analysis of Valsartan Heart Failure Trial data indicated that the quartile of patients with the biggest average(More)
BACKGROUND AND PURPOSE Few data exist for large managed care populations on the occurrence of subsequent acute ischemic events in persons with established atherosclerotic vascular disease. We estimated the occurrence of secondary stroke, acute myocardial infarction (AMI), and vascular deaths among 2 large, managed care samples. METHODS With the use of(More)
BACKGROUND The role of C-reactive protein (CRP) in heart failure is not well studied. We assessed the prognostic value of CRP in patients randomized in Val-HeFT (Valsartan Heart Failure Trial) and studied changes in CRP that were associated with valsartan. METHODS AND RESULTS Characteristics of patients with baseline CRP levels above and below the median(More)
BACKGROUND In 2007, the National Kidney Foundation (NKF) published clinical practice guidelines and recommendations for treating patients with diabetes and kidney diseases. Given recent studies that may enhance our understanding of the benefits and harms of glycemic, lipid, and albuminuria management in patients with diabetes and chronic kidney disease(More)
OBJECTIVES To estimate mortality risk associated with individual commonly prescribed antipsychotics. DESIGN Five-year retrospective study. SETTING Veterans national healthcare data. PARTICIPANTS Predominantly male, aged 65 and older, with a diagnosis of dementia and no other indication for an antipsychotic. Subjects who received an antipsychotic were(More)
BACKGROUND Clostridium difficile infection is increasing in incidence and severity. The optimal treatment is unknown. PURPOSE To determine whether, among adults with C. difficile infection, treatment with certain antibiotics compared with others results in differences in initial cure, recurrence, and harms. DATA SOURCES MEDLINE, AMED,(More)
BACKGROUND Hypothetically, most of the effects of heart failure on quality of life might be attributed to symptoms produced by the pathology. Relationships between measures of these concepts need to be quantified to test this conceptual model. METHODS AND RESULTS Measurements of heart failure pathology and symptoms and quality of life as measured by the(More)