Thomas Roper

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This paper describes our experience in using Aspect Oriented Programming to greatly ease maintenance and evolution tasks in industrial software evolution. We have discovered that AOP can be effectively used to add unpluggable features to an existing code base. AOP has allowed us to place code related to certain features into separate modules, which eases(More)
A convergent synthesis of adenosine A2a agonist 1 in the form of its maleate salt 2 was achieved. The key step in this approach was the highly selective 9beta-glycosylation reaction between 2-haloadenines or an N(2)-alkyl-6-chloroguanine and a D-ribose derivative containing a 2-ethyltetrazolyl moiety. Glycosylations of other purine derivatives were also(More)
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