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  • Paul D. Adams, Ralf W. Grosse-Kunstleve, +7 authors Thomas C. Terwilliger
  • Materials Science, Medicine
  • Acta crystallographica. Section D, Biological…
  • 2002 (First Publication: 1 November 2002)
  • Structural genomics seeks to expand rapidly the number of protein structures in order to extract the maximum amount of information from genomic sequence databases. The advent of several large-scaleExpand
  • Jennifer E. Griffin, Jeffrey D Gawronski, Michael A. DeJesus, Thomas R. Ioerger, Brian J. Akerley, Christopher M. Sassetti
  • Biology, Medicine
  • PLoS pathogens
  • 2011 (First Publication: 1 September 2011)
  • The pathways that comprise cellular metabolism are highly interconnected, and alterations in individual enzymes can have far-reaching effects. As a result, global profiling methods that measure geneExpand
  • Philana Ling Lin, Christopher B. Ford, +6 authors JoAnne L. Flynn
  • Biology, Medicine
  • Nature Medicine
  • 2014 (First Publication: 15 December 2013)
  • Over 30% of the world's population is infected with Mycobacterium tuberculosis (Mtb), yet only ∼5–10% will develop clinical disease. Despite considerable effort, researchers understand little aboutExpand