Thomas R Hansen

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A member of the interferon-stimulated gene (ISG) family encodes a 17-kDa ubiquitin homolog called ISG17 that is induced in the bovine uterine endometrium by interferon-tau (IFN-tau) during early pregnancy. The bovine (b) ISG17 cDNA shares 30% identity with a tandem ubiquitin repeat and 70% identity with human (h) ISG15. The present experiments were designed(More)
Transcriptomal changes in the uterine endometrium induced in response to the implanting embryo remain largely unknown. In this study, using Affymetrix mRNA expression microarray analysis, we identified genes differentially expressed in the murine endometrium in the presence or absence of the embryo. Compared with the pseudopregnant deciduoma induced by a(More)
BACKGROUND The progression of implantation and placentation in ruminants is complex and is regulated by interplay between sex steroids and local signaling molecules, many of which have immune function. Chemokines and their receptors are pivotal factors in implantation and vascularization of the placenta. Based on known critical roles for chemokine receptor(More)
In this paper we reflect on our research into the design and deployment of large interactive displays in hospitals. First, we introduce lessons from studies of the use of large displays to coordinate hospital work in a hectic and critical work environment. Then we present some of our current research, especially focusing on our current design of large(More)
Medical Informatics has traditionally been concerned with optimizing the acquisition, storage, retrieval, and use of information in health and biomedicine. These systems have hence often payed little attention to supporting the collabora-tive nature of most medical work. In this position paper, we want to introduce our ongoing work on CSCW research in a(More)
BACKGROUND Isg15 covalently modifies murine endometrial proteins in response to early pregnancy. Isg15 can also be severed from targeted proteins by a specific protease called Ubp43 (Usp18). Mice lacking Ubp43 (null) form increased conjugated Isg15 in response to interferon. The Isg15 system has not been examined in chorioallantoic placenta (CP) or(More)
1 Preface The Equine Reproduction Laboratory (ERL) has been an active education, research, outreach, and clinical service unit of Colorado State University since 1967. The ERL has evolved significantly through the years and is recognized as one of the premier programs in equine reproduction in the world. The ERL is a unit within the Animal Reproduction and(More)
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