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Thomas Poeschinger

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Werner V. Scheuer10
Vasilis Ntziachristos7
Deborah A. Altomare6
Joseph R. Testa6
Claudia Fumarola5
10Werner Scheuer
7Thomas G. Weber
6Michael Dobosz
5Jerry Eriksson
5Yamini Yadav

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2008
2018
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Co-author

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Bioluminescence Imaging Correlates with Tumor Serum Marker, Organ Weights, Histology, and Human DNA Levels during Treatment of Orthotopic Tumor Xenografts with Antibodies
In this study, we correlate results of bioluminescence measurements with established readouts for assessing therapeutic efficacy of antibodies in orthotopic cancer xenografts. An orthotopic tumor… (More)
Noninvasive Bioluminescence Imaging of AKT Kinase Activity in Subcutaneous and Orthotopic NSCLC Xenografts: Correlation of AKT Activity with Tumor Growth Kinetics1
Aberrant signaling through the AKT kinase mediates oncogenic phenotypes including cell proliferation, survival, and therapeutic resistance. Here, we utilize a bioluminescence reporter for AKT kinase… (More)
Noninvasive monitoring of pharmacodynamics and kinetics of a death receptor 5 antibody and its enhanced apoptosis induction in sequential application with doxorubicin.
Induction of apoptosis plays a crucial role in the response of tumors to treatment. Thus, we investigated the pharmacodynamics and tumor saturation kinetics of a death receptor 5 antibody (anti-DR5)… (More)
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