Thomas P. Wright

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PURPOSE Infantile esotropia is associated with maldevelopment of cortical visual motion processing, manifested as directional asymmetry of motion visual evoked potentials (mVEPs). The purpose of this study was to determine whether early surgery at or before age 11 months could promote the development of cortical visual motion processing in human infants,(More)
1. A passive-avoidance-to-active-avoidance negative transfer paradigm was used to investigate systematically the time-dependent effects of fructose on reactivated memories in rats. 2. Memory reactivation consisted of re-exposing the rats 24 hr after passive-avoidance conditioning to environmental and learning cues present during training; post-reactivation(More)
Immersion freezing is the most relevant heterogeneous ice nucleation mechanism through which ice crystals are formed in mixed-phase clouds. In recent years, an increasing number of laboratory experiments utilizing a variety of instruments have examined immersion freezing activity of atmospherically relevant ice-nucleating particles. However, an(More)
Vigabatrin, a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), is widely used as initial monotherapy in infantile spasms and add on therapy in partial onset seizures. Vigabatrin is associated with retinal toxicity causing constriction of the visual field. Our aim was to assess what effect add-on antiepileptic drug(More)
PURPOSE To identify the genetic cause of autosomal recessive familial foveal retinoschisis (FFR). METHODS A female sibship with FFR was identified (Family-A; 17 and 16 years, respectively); panel based genetic sequencing (132 genes) and comparative genome hybridization (142 genes) were performed. Whole-exome sequencing (WES) was performed on both siblings(More)
—In patients suffering from focal epilepsy, the region of seizure onset is characterized by hyperperfusion during the seizure (ictal state), and hypoperfusion in normal (inter-ictal) state. For diagnosis and surgery planning in epilepsy patients, ictal and inter-ictal SPECT images play a major role. However, comparison of this kind of data is a difficult(More)
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