Thomas P. Powers

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The genealogy of vertebrate Hox genes and clusters has long fascinated evolutionary and developmental biologists alike. The importance of Hox genes is underscored by their involvement in axial patterning, their spatial colinearity of gene order with respect to expression domains and their likely interconnection with morphological evolution [1]. Whereas the(More)
We have generated a BAC library from the Indonesian coelacanth, Latimeria menadoensis. This library was generated using genomic DNA of nuclei isolated from heart tissue, and has an average insert size of 171 kb. There are a total of 288 384-well microtiter dishes in the library (110,592 clones) and its genomic representation is estimated to encompass > or =(More)
The living coelacanth is a lobe-finned fish that represents an early evolutionary departure from the lineage that led to land vertebrates, and is of extreme interest scientifically. It has changed very little in appearance from fossilized coelacanths of the Cretaceous (150 to 65 million years ago), and is often referred to as a "living fossil." An important(More)
The Hox genes have been found to encode transcription factors, which specify the morphological identity of structures along the anteroposterior axis of animals ranging from worms to mice. The canonical set of nine genes is organized in a cluster in the genome of several protostomes and deuterostomes. However, within insects, whereas the Hox genes are(More)
Data on 41 cases (37 intraocular lenses and four globes) of intraocular lenses explanted or expulsed after ocular trauma were retrieved from over 5,000 intraocular lenses and 1,200 globes. The age of the male and female donors varied significantly (male, 64.4 +/- 13.1 years; female, 75.5 +/- 12.6 years; P = .0334). Twenty-two were posterior chamber, 11 were(More)
The authors studied two functioning filtration blebs to evaluate a possible transconjunctival route of aqueous humor flow and describe potential differences between thin cystic and thick opaque functioning filtration blebs. The specimens were prepared for light and electron microscopy immediately after surgical excision because of filtration bleb(More)
We examined and treated four patients with anophthalmic socket pain. Conditions responsible for this problem in this series included scleritis after evisceration, amputation neuroma, pain from a skull-base meningioma, and chemical dependency with drug-seeking behavior. The pain associated with the scleritis after evisceration responded to removal of the(More)
We studied laser suture lysis of subconjunctival scleral sutures in a rabbit eye using selected wavelengths from a dye and diode laser to determine which wavelength caused the least conjunctival damage. We found an oval shaped area of coagulation necrosis surrounding the suture track in the conjunctival substantia propria measuring in depth 61.0 mu for 488(More)
PURPOSE To evaluate differences in the effects of diode and argon trabeculoplasty on cadaver eye trabecular meshwork. METHODS The argon laser was used at a 50 mu spot size, 500 to 100 mW of power, and a 0.1 second time interval, and the diode laser was used at a 0.1 to 0.2 second time interval, 100 mu spot size, and 400 to 1200 mW of power. Analysis was(More)