Thomas P Heffernan

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This study examined population-specific allometric exponents to control for the effect of body mass (BM) on bench press, clean, and squat strength measures among Division I-A collegiate football athletes. One repetition maximum data were obtained from a university pre-season football strength assessment (bench press, n = 207; clean, n = 88; and squat n =(More)
Research into stroke survivors and their partners have shown that the partner frequently rates the stroke survivor as less capable than the survivors rate themselves through self-report questionnaires or qualitative interviews; however, no research to date has used cognitive tasks as a method for in vestigation. This paper aims to investigate if the stroke(More)
Previous studies show that mitochondria adapt to changes of arterial PO2. The present study investigates heart and brain mitochondrial respiratory rate (RR) in 23 guinea pigs at varying blood COHb levels. Blood gases and [COHb] were recorded in all animals. Brain and heart mitochondria were isolated. State 4 RR, state 3 RR with glutamate-malate substrate,(More)
OBJECTIVES The majority of women with Stage III/IV ovarian cancer who achieve clinical complete response with frontline standard of care will relapse within 2years. Vigil immunotherapy, a GMCSF/bi-shRNA furin DNA engineered autologous tumor cell (EATC) product, demonstrated safety and induction of circulating activated T-cells against autologous tumor in(More)
Previous studies have shown that the increased respiratory rate (RR) of newborn and adult brain mitochondria seen in states of reduced arterial O2 tension is an adaptive response. The present study investigates the response of fetal lamb brain mitochondria to decreased O2 content produced by increasing carboxy-hemoglobin concentration [COHb]. Ten(More)
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