Thomas M. Zennie

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Based on the epidemiological evidence for a relationship between consumption of certain foods and decreased cancer incidence in humans, an assay was developed to screen and fractionate plant extracts for chemopreventive potential. This assay measures effects on the metabolism of [3H]benzo(a)pyrene [B(a)P] in hamster embryo cell cultures. Screening of(More)
Bulk dust samples obtained from grain elevators in the central Illinois area were analyzed for aflatoxin (AFT) content using instrumental two-dimensional high performance thin-layer chromatography (HP-TLC). AFT B1 levels ranged from nondetectable up to 3.5 ppb. This is the first report of AFT occurring in dust in northern grain mills. Long-term exposures of(More)
Glucosinolates are common components of cruciferous vegetables that can be hydrolyzed during food processing to yield isothiocyanates, some of which have been shown to inhibit the induction of mammary tumors in rats by 7,12-dimethyl-benz[a]anthracene. To determine how intact glucosinolates affect the metabolism of benzo[a]pyrene (B[a]P) in mammalian cells(More)
Based on the epidemiolÃ3gica! evidence for a relationship between consumption of certain foods and decreased cancer incidence in humans, an assay was developed to screen and fractionate plant extracts for chemopreventive potential. This assay measures effects on the metabo lism of |3H)benzo(a)pyrene [B(a)P] in hamster embryo cell cultures. Screening of(More)
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