Thomas M. Grist

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Anxiety is a debilitating symptom of many psychiatric disorders including generalized anxiety disorder, mood disorders, schizophrenia, and autism. Anxiety involves changes in both central and peripheral biology, yet extant functional imaging studies have focused exclusively on the brain. Here we show, using functional brain and cardiac imaging in sequential(More)
An MR angiographic technique, referred to as 3D TRICKS (3D time-resolved imaging of contrast kinetics) has been developed. This technique combines and extends to 3D imaging several previously published elements. These elements include an increased sampling rate for lower spatial frequencies, temporal interpolation of k-space views, and zero-filling in the(More)
PURPOSE To compare the accuracy of a noninvasive magnetic resonance (MR) imaging method to rapidly determine single-kidney glomerular filtration rate (GFR) relative to findings with an accepted standard of reference. MATERIALS AND METHODS Simultaneous inulin and MR imaging measurements of renal excretory function were performed in six small swine. Renal(More)
The inability to return the heart to the same position for all breath-holds during 2D coronary MR imaging can result in imaging different locations than desired. This can lead to problems such as (i) missing a whole vessel, or a part of it, (ii) misaligning segments of vessels imaged in different breath-holds, and (iii) degrading image quality when a single(More)
PURPOSE To evaluate the imaging performance and patient tolerance of a blood-pool contrast agent (MS-325) for magnetic resonance (MR) angiography. MATERIALS AND METHODS Imaging of peripheral and carotid vessels was performed in seven healthy volunteers in a phase I clinical trial of the gadolinium chelate MS-325. Each volunteer received an intravenous(More)
Recent developments in renal magnetic resonance angiography have led to a significant improvement in the technical success rate and diagnostic accuracy of the methods. Specifically, three-dimensional contrast-enhanced magnetic resonance angiography methods have been shown to provide a more reliable depiction of renal artery morphology than older techniques.(More)
We compared the efficacy of MR angiography with that of conventional angiography for visualizing the renal arteries and detecting renovascular disease. Thirty-three MR angiographic studies, consisting of axial two-dimensional (2-D) phase-contrast, coronal 2-D phase-contrast, and coronal 2-D time-of-flight acquisitions, were performed within 48 hr of(More)
Focal infarction of skeletal muscle is a complication of diabetes mellitus. In the appropriate clinical setting and with characteristic magnetic resonance imaging (MRI) findings, prompt diagnosis can prevent unnecessary morbidity by avoiding excisional biopsy. We report a case of diabetic muscular infarction presenting as a painful thigh mass and review(More)
A surface coil assembly consisting of two interleaved coplanar resonators that are intrinsically decoupled from each other is described for imaging at 1.5 T. Vector reception fields on-axis at 3 cm depth are orthogonal and of equal magnitude. Both components of magnetization were received and combined resulting in a 2 1/2 improvement in signal-to-noise for(More)
Undersampled projection reconstruction (PR) is investigated as an alternative method for MRA (MR angiography). In conventional 3D Fourier transform (FT) MRA, resolution in the phase-encoding direction is proportional to acquisition time. Since the PR resolution in all directions is determined by the readout resolution, independent of the number of(More)