Thomas Lee Jacobs

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We tested the hypothesis that muscle fatigue would attenuate vasodilatory responsiveness throughout the resistance network. The retractor muscle of anaesthetized hamsters was contracted (once per 2 s for 1 min) at duty cycles of 2.5, 10 and 20 % before and after fatiguing contractions that diminished peak tension and muscle glycogen by >50 %. Arterioles and(More)
1. Vasodilatation initiated by contracting skeletal muscle 'ascends' from the arteriolar network to encompass feed arteries. Acetylcholine delivery from a micropipette onto a feed artery evokes hyperpolarisation at the site of application; this signal can conduct through gap junctions along the endothelium to produce vasodilatation. We tested whether(More)
We have studied the structures produced when nonbiological samples were subjected to quick-freezing and freeze-drying with a liquid helium cooled freeze-slamming device. Samples examined in this way included sodium chloride, sucrose, and Tris buffer. A variety of filamentlike and trabeculumlike structures were formed in these preparations. These structures(More)
Low Plasticity Burnishing (LPB) has been applied to produce a layer of deep high magnitude compressive residual stress in the leading edge of Ti-6Al-4V first stage fan blades. The goal was to improve damage tolerance from 0.13 to 0.5 mm (0.005 to 0.02 in.). LPB processing of the airfoil surface was performed on a conventional four-axis CNC mill. The LPB(More)
Neuromuscular activation is a primary determinant of metabolic demand and oxygen transport. The m. retractor and m. epitrochlearis are model systems for studying metabolic control and oxygen transport; however, the organization of muscle fibers and motor nerves in these muscles is unknown. We tested whether the topology of motor innervation was related to(More)
We present a strongly interacting quadruple system associated with the K2 target EPIC 220204960. The K2 target itself is a Kp = 12.7-mag star at Teff 6100 K, which we designate as ‘B-N’ (blue northerly image). The host of the quadruple system, however, is a Kp 17-mag star with a composite M-star spectrum, which we designate as ‘R-S’ (red southerly image).(More)
The census of exoplanets is incomplete for orbital distances larger than 1 AU. Here, we present 41long-period planet candidates in 38systems identified by Planet Hunters based on Kepler archival data (Q0–Q17). Among them, 17exhibit only one transit, 14have two visible transits, and 10have more than three visible transits. For planet candidates with(More)