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  • Jian Ye, George Coulouris, Irena Zaretskaya, Ioana Cutcutache, Steve Rozen, Thomas L. Madden
  • Biology, Medicine, Computer Science
  • BMC Bioinformatics
  • 2012 (First Publication: 18 June 2012)
  • BackgroundChoosing appropriate primers is probably the single most important factor affecting the polymerase chain reaction (PCR). Specific amplification of the intended target requires that primersContinue Reading
  • Alejandro A. Schäffer, L. Aravind, +5 authors Stephen F. Altschul
  • Medicine, Biology
  • Nucleic acids research
  • 2001 (First Publication: 15 July 2001)
  • PSI-BLAST is an iterative program to search a database for proteins with distant similarity to a query sequence. We investigated over a dozen modifications to the methods used in PSI-BLAST, with theContinue Reading