Learn More
Bourjault has presented a method which will generate all valid assembly sequences for the set of parts that constitute an assembly. A modification of Bourjault's method is presented which makes practical the application of this technique of assembly analysis to assemblies with greatly increased part count. The salient difference between the two methods is(More)
A freezing probe was placed on the skull of postnatal day (PN) 1 rats to induce formation of a cerebrocortical microsulcus. Experimental studies were performed on PN days 21-24. At that time point, Nissl-stained sections revealed the presence of a microsulcus similar to that described in human dysplastic cortex. Immunocytochemical staining for parvalbumin,(More)
Pharmacological modulation of gamma-aminobutyric acid-A (GABAA) receptors can provide important information on the types of subunits composing these receptors. In recombinant studies, zinc more potently inhibits alphabeta subunits compared with the alphabetagamma combination, whereas modulation by nanomolar concentrations of the benzodiazepine type(More)
1. The influence of age on striatal neuron Ca2+ physiology was studied through an analysis of intracellularly recorded Ca(2+)-mediated plateau potentials. In vitro brain slices from young and aged rats were treated with the K+ channel blocker tetraethylammonium (30 mM) to facilitate the expression of plateau potentials. A sample of neurons was also filled(More)
This paper describes a prototype software system that implements a form of feature-based design for assembly. It is not an automated design system but instead a decision and design aid for designers interested in Concurrent Design. Feature-based design captures design intent (assembly topology, product function, manufacturing, or field use) while creating(More)
Calcium channels play an important role in generating the complex electrophysiology of dopaminergic (DAergic) neurons in the substantia nigra pars compacta (SNc). To directly study these calcium currents in dendritically intact neurons, two issues needed to be addressed: the identity of the neuron (DAergic versus non-DAergic) and control of putative(More)
The design of an assembly system is a complex problem, often requiring large teams of engineers with significant experience and expertise. Based on studies of the product design, these teams must select an assembly sequence, generate a corresponding process plan, identify the resources capable of completing the tasks in the process plan, and group these(More)