Thomas Krzizok

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Pericyte loss is an early pathologic feature of diabetic retinopathy, consistently present in retinae of diabetic humans and animals. Because pericyte recruitment and endothelial cell survival are controlled, in part, by the angiopoietin/Tie2 ligand/receptor system, we studied the expression of angiopoietin-2 and -1 in relation to the evolution of pericyte(More)
AIMS To develop appropriate methods of eye muscle surgery in highly myopic patients with esotropia and hypotropia, with respect to the pathological findings in high resolution magnetic resonance imaging (MRI). METHODS 35 patients with unilateral or bilateral high myopia and strabismus--that is, axial length of the globe averaged 29.4 mm. Multiple coronal,(More)
  • T Krzizok
  • Der Ophthalmologe : Zeitschrift der Deutschen…
  • 2007
Botulinum toxin treatment was originally developed 25 years ago by Alan B. Scott to produce reversible weakening of extraocular eye muscles in humans (chemodenervation). The following uses are still helpful today in comparison with eye muscle surgery, prism applications etc.: Preoperative evaluation of possible postoperative diplopia in patients in whom(More)
Superior oblique myokymia (SOM) is a rare eye movement disorder presenting as uniocular rotatory microtremor due to intermittent contractions of the superior oblique muscle. Medical treatment usually fails to provide long-term benefit for the patient and has considerable side effects. Surgical alternatives including tenotomy or partial tenectomy of the(More)
Superior oblique myokymia (SOM) is an ocular motility disorder characterized by oscillopsia, vertical or torsional diplopia, sometimes combined with pressure sensation. Although the pathophysiological basis is unclear, isolated case reports have documented its association with intracranial pathological processes. We present a case of SOM associated with a(More)
PURPOSE Positionally induced cyclotorsion could be an important factor concerning correction of astigmatism in refractive surgery. The method of binocular three dimensional infrared video-oculography (3D-VOG) was used to determine a possible influence of body position on cyclotorsion. METHODS 38 eyes (19 healthy subjects, median value of age 25.5) with(More)
PURPOSE To analyze the path of extraocular muscles (EOMs) quantitatively in highly myopic subjects with and without restricted eye motility versus control. To elucidate the cause of the acquired motility disorder in patients with high myopia. METHODS Thirty-three orbits were imaged using a Magnetom or Siemens Vision (Siemens, Erlangen, Germany; both 1.5(More)
BACKGROUND Congenital or acquired anomalous synkinetic movements are common in Neuro-Ophthalmology. Examples are the Stilling-Türk-Duane syndrome, the Marcus Gunn phenomenon or secondary oculomotor synkinesis in oculomotor nerve palsy. PATIENT AND METHOD A 29-year-old woman with N.V-, N.VI-, N.VII- and N.VIII-lesion after blunt cranio-cerebral trauma(More)
BACKGROUND The head-tilt phenomenon (difference between the vertical deviations with an ipsilateral and contralateral head-tilt by 45 deg. each) occurring in patients with a superior oblique palsy has traditionally been explained by the lacking contraction of the superior oblique muscle within the synkinetic movement of ocular counterrolling. However, using(More)