Thomas Jonsson

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BACKGROUND Previous studies suggest that visceral ischaemia precedes shock and multiple organ failure, though methods for studying humans are lacking. We aimed to evaluate intraperitoneal microdialysis, a new technique for detecting splanchnic ischaemia in clinical practice. METHODS Right-sided hemicolectomy was performed in eight patients who were(More)
With the goal of developing a pH-responsive micelle system, linear-dendritic block copolymers comprising poly(ethylene oxide) and either a polylysine or polyester dendron were prepared and hydrophobic groups were attached to the dendrimer periphery by highly acid-sensitive cyclic acetals. These copolymers were designed to form stable micelles in aqueous(More)
AIM Trials have reported clinical improvement and reduced need for amputation in critical limb ischemia (CLI) patients receiving therapeutic angiogenesis with stem cells. Our objective was to test peripheral stem cell therapy efficacy and safety to gain experiences for further work. METHODS We included nine CLI patients (mean age 76.7 ±9.7). Stem cells(More)
PURPOSE To report the successful endovascular treatment of a ruptured thoracic aortic aneurysm during cardiopulmonary resuscitation. CASE REPORT A 72-year-old woman with a type B aortic dissection treated conservatively for 8 years was referred for rupture of a 16-cm aneurysm of the descending thoracic aorta. During transfer to the operating room, the(More)
Models describing the relation between impact speed and fatality risk for pedestrians struck by a motor vehicle have frequently been used by practitioners and scientists in applying an S curve to visualize the importance of speed for the chance of survival. Recent studies have suggested that these risk curves are biased and do not give representative risk(More)
Patients suffering from critical limb ischemia (CLI) have poor wound healing in the ankle and foot areas. Secondary wound infections are frequent and often treated with prolonged courses of antibiotics. This study set out to investigate to what extent the unbound fraction of 4 g of cloxacillin i.v. reaches its target organ in poorly vascularized tissues,(More)
The sustainability challenge includes a need for new resources. Therefore it is important to show added resource values in sustainability assessments. At the university in Dalarna we use this view, and problem based learning on industrial projects, in environmental management courses. The experiences from those courses, and modelling at Chalmers, indicate(More)
An inexpensive, silent, maintenance-free suction/adsorption system is described for efficiently collecting submicrogram quantities of odors over a wide range of volatilities under field conditions. The samples can later be submitted to gas chromatographic-mass spectrometric analyses. An example is given with odors sampled from solitary bees engaged in(More)
PURPOSE To evaluate the splanchnic and limb metabolic effects of open repair (OR) of abdominal aortic aneurysms (AAA) versus endovascular aneurysm repair (EVAR) in a pilot study utilizing microdialysis. METHODS Nine AAA patients (8 men; mean age 74 years, range 61-85) were treated with EVAR and 9 had an OR (5 men; mean age 70 years, range 55-85). In the(More)
This paper deals with environmental policy in an economic federation, where each national government faces a mixed tax problem. We assume that the federal government sets emission targets, which are implemented at the national level. We also assume that the economic federation is decentralized, meaning that the national governments are first movers(More)
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