Thomas J. Van Winkle

Learn More
Nucleus cuneatus projections to nucleus ventralis posterolarteralis pars medialis (VPLm) and other thalamic as well as midbrain and medullary nuclei were studied in cats using the Fink-Heimer I silver technique. Single electrolytic lesions of very small size were made stereotaxically in different zones of nucleus cuneatus under electrophysiological control.(More)
A recessively inherited hypertrophic neuropathy was discovered in Tibetan Mastiff dogs. Affected pups developed a generalized weakness with hyporeflexia shortly after weaning. Diagnostic findings in 10-18-week-old pups included: moderate to severe reduction in nerve conduction velocities, infrequent denervation potentials, and inconstant elevation in CSF(More)
In the adult rodent brain, neural progenitor cells migrate from the subventricular zone of the lateral ventricle towards the olfactory bulb in a track known as the rostral migratory stream (RMS). To facilitate the study of neural progenitor cells and stem cell therapy in large animal models of CNS disease, we now report the location and characteristics of(More)
The pathophysiology of canine diabetes remains poorly understood, in part due to enigmatic clinical features and the lack of detailed histopathology studies. Canine diabetes, similar to human type 1 diabetes, is frequently associated with diabetic ketoacidosis at onset or after insulin omission. However, notable differences exist. Whereas human type 1(More)
  • 1