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Proteophosphoglycans are an expanding family of highly glycosylated Leishmania proteins with many unusual and some unique structural features. The novel protein-glycan linkage in proteophosphoglycans(More)
Isoxazolines are a novel class of parasiticides that are potent inhibitors of γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and L-glutamate-gated chloride channels (GluCls). In this(More)
The abundant surface glycoconjugate of Leishmania promastigotes, lipophosphoglycan (LPG), forms a blue-colored complex (lambda max = 649 nm) with the cationic dye Stains-all, which can be quantitated(More)