Learn More
Active Bacterial Core surveillance (ABCs) is a collaboration between the Centers for Disease Control and Prevention and several state health departments and universities participating in the Emerging Infections Program Network. ABCs conducts population-based active surveillance, collects isolates, and performs studies of invasive disease caused by(More)
We measured reflectance changes by means of optical imaging of intrinsic signals to study the topography of the paw representations in rat somatosensory cortex. Following circumscribed tactile stimulation of single digits or pads, we found large and partially overlapping areas of reflectance changes (delta R). The diameters of their focal zones defined at(More)
It is well-known that the fertility of schizophrenic patients, particularly males, is below the population average. The main measures of fertility (reproductivity) are marriage rate, marital fertility, and rate of reproduction. A review of the literature reveals the rate of reproduction of schizophrenic patients to be 30% to 80% of the general population,(More)
BACKGROUND AND PURPOSE Thrombin-induced clots used in experimental thromboembolic stroke differ from clots forming spontaneously under clinical conditions. We investigated whether this difference influences the efficacy and outcome of thrombolytic treatment. METHODS In rats, the middle cerebral artery was occluded by intracarotid injection of fibrin-rich(More)
We studied phenomena, constraints, rules, and implications of cortical plastic reorganization produced by input coactivation patterns in primary somatosensory cortex of adult rats. Intracortical microstimulation (ICMS) and an associative pairing of tactile stimulation (PPTS) induced plastic changes within minutes to hours that were fully reversible.(More)
We measured reflectance changes by means of optical imaging of intrinsic signals to study the effects of acute electrical cochlear stimulation on the topography of the cat auditory cortex. After single-pulse electrical stimulation at selected sites of a multichannel implant device, we found topographically restricted response areas representing mainly the(More)
OBJECTIVE To study the effects of electrical stimulation on cortical activation patterns. MATERIALS AND METHODS Optical imaging of auditory cortex in cats that are acutely and chronically electrically stimulated with cochlear implants. RESULTS Chronic electrical stimulation results in expansion of cortical territory and overlap. CONCLUSION Effects of(More)
A novel photothrombotic ring stroke model was characterized by multiparametric magnetic resonance imaging, imaging of cerebral blood flow (CBF), adenosine triphosphate (ATP), pH, and histology. Ischemia was initiated by transosseous irradiation of a predefined brain area intravenously perfused by the photosensitive dye erythrosin B in male Wistar rats. In(More)
PURPOSE The aim of this study is the development of a three-dimensional multicellular spheroid cell culture model for the longitudinal comparative and large-scale screening of cancer cell proliferation with noninvasive molecular imaging techniques under controlled and quantifiable conditions. PROCEDURES The human glioblastoma cell line Gli36DeltaEGFR was(More)