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Active Bacterial Core surveillance (ABCs) is a collaboration between the Centers for Disease Control and Prevention and several state health departments and universities participating in the Emerging Infections Program Network. ABCs conducts population-based active surveillance, collects isolates, and performs studies of invasive disease caused by(More)
We measured reflectance changes by means of optical imaging of intrinsic signals to study the topography of the paw representations in rat somatosensory cortex. Following circumscribed tactile stimulation of single digits or pads, we found large and partially overlapping areas of reflectance changes (delta R). The diameters of their focal zones defined at(More)
We studied phenomena, constraints, rules, and implications of cortical plastic reorganization produced by input coactivation patterns in primary somatosensory cortex of adult rats. Intracortical microstimulation (ICMS) and an associative pairing of tactile stimulation (PPTS) induced plastic changes within minutes to hours that were fully reversible.(More)
Soil conservation approaches and agroforestry systems can play an important role in controlling erosion from tropical hillside cropping systems. Experimental testing of their potential application domain and design, however, is costly and time consuming. We, therefore, tested the ability of the Water, Nutrient and Light Capture in Agroforestry Systems(More)
Competition for nutrients and water between crops and associated hedgerows reduces overall performance of contour hedgerow systems and hampers its acceptance by rural communities in tropical mountainous regions. Therefore, it is imperative to better understand competition leading to a decline in crop response close to hedges. In the highlands of North East(More)
BACKGROUND AND PURPOSE Thrombin-induced clots used in experimental thromboembolic stroke differ from clots forming spontaneously under clinical conditions. We investigated whether this difference influences the efficacy and outcome of thrombolytic treatment. METHODS In rats, the middle cerebral artery was occluded by intracarotid injection of fibrin-rich(More)
Magnetic resonance angiography (MRA) was performed in a thromboembolic stroke model of the rat to characterize intracranial vessel occlusion patterns and to test its predictive power for tissue recovery after recombinant tissue plasminogen activator (rt-PA) treatment. After rt-PA-treated selective middle cerebral artery (MCA) occlusion, full recanalization(More)
Numerous allelic variants identified in the familial breast cancer and DNA repair genes BRCA1 and BRCA2 are of unknown impact on protein function or clinical relevance, referred to as unclassified variants (UCV). Lymphocytes from pathogenic BRCA1/2 mutation carriers exhibit an increased level of chromosomal damage after irradiation. We established a(More)
The aim of this study is the development of a three-dimensional multicellular spheroid cell culture model for the longitudinal comparative and large-scale screening of cancer cell proliferation with noninvasive molecular imaging techniques under controlled and quantifiable conditions. The human glioblastoma cell line Gli36ΔEGFR was genetically modified to(More)
OBJECTIVE To study the effects of electrical stimulation on cortical activation patterns. MATERIALS AND METHODS Optical imaging of auditory cortex in cats that are acutely and chronically electrically stimulated with cochlear implants. RESULTS Chronic electrical stimulation results in expansion of cortical territory and overlap. CONCLUSION Effects of(More)