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OBJECTIVE To assess pinopode formation in human endometrium during the luteal phase of the menstrual cycle and in the first trimester of pregnancy. DESIGN Prospective clinical study. SETTING Outpatient infertility clinics and outpatient family planning clinic. PATIENT(S) Thirty-two regularly cycling infertile women, 15 regularly cycling fertile women,(More)
OBJECTIVE To compare DNA damage in ejaculated and testicular spermatozoa in patients with previously unsuccessful oral antioxidant treatment. DESIGN Prospective clinical study. SETTING University-affiliated teaching hospital. PATIENT(S) Twelve men with persistently high sperm DNA damage. INTERVENTION(S) Evaluation of DNA damage of ejaculated and(More)
BACKGROUND The age-related reduction in live-birth rate is attributed to a high rate of aneuploidy and follicle depletion. We showed in an animal model that treatment with Coenzyme Q10 (CoQ10) markedly improved reproductive outcome. The aim of this study was to compare the post-meiotic oocyte aneuploidy rate in in vitro fertilization (IVF) and intra(More)
A guide to Advanced Maternal Age for Ontario service providers, including a summary of statistical trends, influencing factors, health benefits, health risks and recommendations for care. Best Start is grateful to the following people for sharing their expertise as advisors, key informants and expert reviewers in the development of this manual: Best Start(More)
BACKGROUND Reduced female fertility in CF is believed to be due to thick cervical mucous, poor nutritional status, functional hypogonadotropic hypogonadism and possibly increased inflammation. Literature suggests that reduced ovarian reserve may also play a role. METHODS 20 women with CF and 20 controls age 18-35 years were recruited. Serum anti-mullerian(More)
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