Thomas G. Lowe

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BACKGROUND The lack of a reliable, universally acceptable system for classification of adolescent idiopathic scoliosis has made comparisons between various types of operative treatment an impossible task. Furthermore, long-term outcomes cannot be determined because of the great variations in the description of study groups. METHODS We developed a new(More)
STUDY DESIGN Retrospective review of anterior and posterior fusions for treatment of adolescent idiopathic thoracic scoliosis. OBJECTIVES To evaluate both the instrumented thoracic and the spontaneous lumbar curve corrections after treatment of the primary thoracic scoliosis by either anterior or posterior fusion. SUMMARY OF BACKGROUND DATA Recent(More)
STUDY DESIGN A multicenter study of the outcomes of the surgical treatment of adolescent idiopathic scoliosis using the Scoliosis Research Society Questionnaire (SRS 24). OBJECTIVE To evaluate the patient based outcome of the surgical treatment of adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA A paucity of information exists with respect to(More)
Current population studies characterize idiopathic scoliosis as a single-gene disorder that follows the patterns of mendelian genetics, including variable penetrance and heterogeneity. The role of melatonin and calmodulin in the development of idiopathic scoliosis is likely secondary, with indirect effects on growth mechanisms. Reported abnormalities of(More)
STUDY DESIGN An outcome questionnaire was constructed to evaluate patient satisfaction and performance and to discriminate among patients with adolescent idiopathic scoliosis. OBJECTIVES To determine reliability and validity in a new quality-of-life instrument for measuring progress among scoliosis patients. SUMMARY OF BACKGROUND DATA Meta-analysis of(More)
STUDY DESIGN This study compared preoperative and postoperative saggittal curves and spinal balance in patients undergoing spinal fusion with Cotrel-Dubousset instrumentation for severe kyphosis secondary to Scheuermann's disease. Also determined was patient satisfaction regarding relief of pain and correction of the deformity. Thirty two patients with(More)
STUDY DESIGN An in vitro biomechanical investigation to quantify the endplates resistance to compressive loads, in the thoracic and lumbar spine. Comparisons were made to determine the regional strength of the endplate, the optimal size and geometry of interbody support, and the effects of endplate removal on structural strength. OBJECTIVES To(More)
STUDY DESIGN This was a prospective study of two cohort groups of patients (one group receiving anterior instrumentation and the other posterior instrumentation) receiving treatment for thoracic idiopathic scoliosis. OBJECTIVE To present the 2-year postoperative results of a prospective multicenter study comparing the use of anterior instrumentation with(More)
STUDY DESIGN Retrospective case-control series. OBJECTIVE The purpose of this study is to determine whether perioperative complications alter subsequent clinical outcome measures in adult spinal deformity surgery. SUMMARY OF BACKGROUND DATA Increasingly, the benefit of surgical intervention is being evaluated based on patient reported outcomes and(More)
BACKGROUND Previous research has suggested a correlation between pulmonary impairment and thoracic spinal deformity. The curve magnitude, number of involved vertebrae, curve location, and decrease in thoracic kyphosis independently contribute to pulmonary impairment, but the strength of these associations has been variable. The objectives of this study were(More)