Learn More
Saccade characteristics in response to moving and stationary targets were studied in three monkeys (Macaca mulatta) that had been trained to look at a target, which after an initial jump either remained in place or moved forward or backward with constant velocity (10 degrees /s). Eye movements were recorded using a search coil. The contribution of smooth(More)
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been shown to be an effective treatment for Parkinson's disease (PD). The intraoperative positioning of DBS electrodes and postoperative adjustment of the stimulation parameters, however, require continuous, precise evaluation. Moreover, ambulatory measurements of the symptoms would also help(More)
The caudal fastigial nucleus (cFN) is one of the main cerebellar areas involved in the control of eye movements. Lesions of this area cause hypermetria of ipsilateral saccades and hypometria of contralateral saccades, as well as cogwheel smooth pursuit. Most studies with nonhuman primates described this dysmetria with a change of the ratio target amplitude(More)
The development of oculomotor research is closely related to the development of the technology of eye movement recordings. The first part of this chapter summarizes some cornerstones of the history of eye movement recordings from the 18th century until today and explains the technical principles of the early antecedents of modern recording devices. The four(More)
This study investigated the effect of cerebellar lesions on temporal prediction and coordination in eye and hand movements. Nine patients with cerebellar lesions were compared to controls while they made saccades with and without simultaneous pointing movements towards a target that was either temporally predictable or non-predictable. The direction and(More)
Information about the future trajectory of a visual target is contained not only in the history of target motion but also in static visual cues, e.g., the street provides information about the car's future trajectory. For most natural moving targets, this information imposes strong constraints on the relation between velocity and acceleration which can be(More)
Binocular yoking of saccades is essential for single vision of words during reading. This study examines the quality of binocular coordination in individuals with dyslexia, independent of the process of reading. Fifteen dyslexia children (11.2+/-1.4 years) and 15 non-dyslexia individuals (8 children, aged 11.1+/-1.3 years, and 7 adults, 24+/-3 years) were(More)
Eye-hand coordination was investigated with the global effect paradigm. In this paradigm, saccades typically land in between the target and a nearby presented distractor, the configuration's center of gravity. This so-called global effect, or spatial averaging, is attributed to incomplete target selection. Four experiments demonstrated a similar effect for(More)
Neuronal tuning functions can be expressed by the conditional probability of observing a spike given any combination of explanatory variables. However, accurately determining such probabilistic tuning functions from experimental data poses several challenges such as finding the right combination of explanatory variables and determining their proper neuronal(More)
Anticipatory pursuit is not exclusively based on the recent history of target motion ("temporal anticipation"): it can also use static visual cues ("non-temporal anticipation"). Large non-temporal anticipatory changes of the direction of smooth pursuit are observed when the future trajectory of the target can be inferred from a visual "path cue" (Ladda et(More)