Thomas Ebner

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In contrast to IVF, in ICSI the surrounding cumulus and corona cells must be removed completely, as only denuded oocytes can be successfully manipulated by the holding pipette. This ancillary effect of ICSI allows us to focus on the morphology of preimplantation development from the earliest stages. Early prognosis regarding the developmental fate of(More)
This prospective study tested a new type of culture dish for the effects of individual culture and autotrophic factors. Within a 6-month period, 72 patients with nine or more fertilized eggs were enrolled in this prospective evaluation. Their 936 zygotes were split into three subgroups (individual culture, individual culture with contact to neighbours,(More)
Children of a heterozygous parent are expected to carry either allele with equal probability. Exceptions can occur, however, due to meiotic drive, competition among gametes, or viability selection, which we collectively term "transmission distortion" (TD). Although there are several well-characterized examples of these phenomena, their existence in humans(More)
Few cytoplasmic dysmorphisms of oocytes have been reported to negatively influence the further fate of the ova. One such anomaly, namely the central aggregation of the smooth endoplasmic reticulum (SER), has recently been associated with suboptimal outcome in a limited number of patients. In order to increase prognostic value, it was decided to(More)
OBJECTIVE Since little is known about the actual incidence and fate of vacuoles at different stages of development this preliminary study was set up to accurately measure vacuoles and track them to day 5. DESIGN Prospective study. SETTING Women's General Hospital in Austria. PATIENT(S) A total of 223 consecutive IVF and intracytoplasmic sperm(More)
BACKGROUND Serum anti-Müllerian hormone (AMH) levels provide a powerful means for predicting ovarian response, which is reflected not only by the size of the primordial follicle pool but also by the quality of the oocytes. Considering a mutual interdependence between AMH-expressing somatic cells and gametes, this prospective morphological study was set up(More)
The association between oocyte morphology and subsequent fertilization rate and embryo quality in intracytoplasmic sperm injection (ICSI) is subject to considerable controversy. This retrospective study was carried out to investigate a possible prognostic value of first polar body morphology with regard to fertilization rate and embryo quality. A total of(More)
OBJECTIVE To determine the impact of embryo fragmentation on pregnancy, obstetric, and perinatal outcome. DESIGN Retrospective analysis of embryo transfers that were homogeneous in regard to the degree of fragmentation. SETTING Fertility center. PATIENT(S) A cohort of 460 fresh embryo transfers. INTERVENTION(S) A total of 164 pregnancies were(More)
Metaphase II-stage oocytes collected from patients following ovarian stimulation show varying qualities. Both nuclear and cytoplasmic maturation have to be completed in a co-ordinated mode to ensure optimal conditions for subsequent fertilization. Disturbances or asynchrony of these processes may result in different morphological abnormalities, depending on(More)
OBJECTIVE To compare the outcome of singleton pregnancies originating from a twin gestation with singleton pregnancies originating from a single gestation. DESIGN Case-control study. SETTING Women's general hospital in Austria. PATIENT(S) A total of 794 singleton deliveries after IVF/intracytoplasmic sperm injection, including 46 survivors of(More)