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  • Christian Popp, Valentin Gorboulev, Thomas Dr Dipl-Chem Mueller, Dmitry Gorbunov, Natalia V. Shatskaya, Hermann Koepsell
  • Biology, Medicine
  • Molecular pharmacology
  • 2005 (First Published: 1 May 2005)
  • To identify functionally relevant amino acids in the rat organic cation transporter 1 (rOCT1), 18 consecutive amino acids in the presumed fourth transmembrane alpha helix (TMH) were mutated andContinue Reading
  • Dmitry Gorbunov, Valentin Gorboulev, +4 authors Hermann Koepsell
  • Chemistry, Medicine
  • Molecular pharmacology
  • 2008
  • Voltage-clamp fluorometry was performed with a cysteine-deprived mutant of rat organic cation transporter 1 (rOCT1) in which Phe483 in transmembrane alpha-helix (TMH) 11 close to the extracellularContinue Reading
  • Elizabeth S. Withers-Ward, Thomas Dr Dipl-Chem Mueller, Isabel S. Chen, Juli Feigon
  • Medicine, Chemistry
  • Biochemistry
  • 2000 (First Published: 11 February 2000)
  • The DNA repair protein HHR23A is a highly conserved protein that functions in nucleotide excision repair. HHR23A contains two ubiquitin associated domains (UBA) that are conserved in a number ofContinue Reading
  • Christopher Volk, Valentin Gorboulev, Alexander Kotzsch, Thomas Dr Dipl-Chem Mueller, Hermann Koepsell
  • Biology, Medicine
  • Molecular pharmacology
  • 2009 (First Published: 1 August 2009)
  • We have shown previously that Leu447 and Gln448 in the transmembrane helix (TMH) 10 of rat organic cation transporter rOCT1 are critical for inhibition of cation uptake by corticosterone. Here, weContinue Reading