Thomas Dousa

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We investigated the dependence of nicotinate-adenine dinucleotide phosphate (NAADP)-induced Ca2+ release from intracellular stores of sea urchin egg homogenates, upon extravesicular Ca2+. In contrast to the Ca2+ release induced inositol 1',4',5'-triphosphate (IP3) or cyclic ADP-ribose (cADPR), the Ca2+ release induced by NAADP was completely independent of(More)
News in Physiological Sciences (ISSN 0886-1714) is published bimonthly (one volume per year) by the International Union of Physiological Sciences and the American Physiological Society. Copyright 0 1989 by the International Union of Physiological Sciences and the American Physiological Society. Printed in the United States of America. The code at the bottom(More)
To survey the presence of the four different isoforms of the plasma membrane calcium pump (PMCA) and their alternative splicing variants in the rat kidney, three major zones (cortex, outer medulla, and inner medulla) were macrodissected and probed for the presence of mRNA encoding these isoforms and their variants at the splicing site C by using reverse(More)
so many interpretations and judgments possible? Is it the fact that OMAM is a play in narrative form, consisting almost entirely of dialogue? Is it because of the range of characters, including the two leads but also the ranch owner, his son Curley, Curley's young wife, a black hand, an idealized cowboy, and others? Certainly the novel allows schoolchildren(More)
Serotonin (5-HT) was recently reported to inhibit cAMP generation in oppossum (OK) cells. We thus investigated the effects of 5-HT upon the Na(+)-Pi cotransport in cultured OK cells and its interactions with dopamine. Incubation of OK cells with 1 nM-10 microM 5-HT resulted in dose-dependent stimulation of Na(+)-Pi contransport (ED50 approximately equal to(More)
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