Thomas Crowell

Steve Perrin2
Mitchell Reff1
John M McCoy1
Richard L Cate1
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Axon regeneration in the adult CNS is prevented by inhibitors in myelin. These inhibitors seem to modulate RhoA activity by binding to a receptor complex comprising a ligand-binding subunit (the Nogo-66 receptor NgR1) and a signal transducing subunit (the neurotrophin receptor p75). However, in reconstituted non-neuronal systems, NgR1 and p75 together are(More)
  • Matvey Lukashev, Doreen LePage, Cheryl Wilson, Véronique Bailly, Ellen Garber, Alex Lukashin +28 others
  • 2006
The lymphotoxin-beta receptor (LT beta R) is a tumor necrosis factor receptor family member critical for the development and maintenance of various lymphoid microenvironments. Herein, we show that agonistic anti-LT beta R monoclonal antibody (mAb) CBE11 inhibited tumor growth in xenograft models and potentiated tumor responses to chemotherapeutic agents. In(More)
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