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Previous work in our laboratory has shown that microvascular pericytes sort muscle and nonmuscle actin isoforms into discrete cytoplasmic domains (Herman, I. M., and P. A. D'Amore. 1985. J. Cell Biol. 101:43-52; DeNofrio, D.T.C. Hoock, and I. M. Herman. J. Cell. Biol. 109:191-202). Specifically, muscle (alpha-smooth) actin is present on the stress fibers(More)
We have recently cloned and characterized ankyrin-3 (also called ankyrin(G)), a new ankyrin that is widely distributed, especially in epithelial tissues, muscle, and neuronal axons (Peters, L.L., K.M. John, F.M. Lu, E.M. Eicher, A. Higgins, M. Yialamas, L.C. Turtzo, A.J. Otsuka, and S.E. Lux. 1995. J. Cell Biol. 130: 313-330). Here we show that in mouse(More)
  • Thomas C Hoock, Patricia M Newcomb, Ira M Herman, Herman, T C Hoock, I M J Herman
  • 2002
Previous work in our laboratory has shown that microvascular pericytes sort muscle and nonmus-cle actin isoforms into discrete cytoplasmic domainsally, muscle (ix-smooth) actin is present on the stress fibers while nonmuscle actins (/3 and 3') are located on stress fibers and in regions of moving cytoplasm (e.g., ruffles, lamellae). To determine the form(More)
We characterized the form and distribution of muscle and nonmuscle actin within retinal pericytes. Antibodies with demonstrable specificities for the actin isoforms were used in localization and immunoprecipitation experiments to identify those cellular domains that were enriched or deficient in one or several actin isoforms. Living pericyte behavior was(More)
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