Thomas B. Newman

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CONTEXT Half of all cases of cerebral palsy (CP) occur in term infants, for whom risk factors have not been clearly defined. Recent studies suggest a possible role of chorioamnionitis. OBJECTIVE To determine whether clinical chorioamnionitis increases the risk of CP in term and near-term infants. DESIGN, SETTING, AND PATIENTS Case-control study nested(More)
OBJECTIVE The purpose of this work was to study risk factors and neuroimaging characteristics of cerebral palsy in term and near-term infants. PATIENTS AND METHODS Among a cohort of 334,339 infants > or = 36 weeks' gestation born at Kaiser Permanente Medical Care Program in northern California in 1991-2003, we identified infants with cerebral palsy and(More)
A b s t r a c t We evaluated the ability of a microcomputer program (Automatch) to link patient records in our hospital's database (N = 253,836) with mortality files from California in-hospital deaths, 99.3% for patients with social security numbers. None of 14,073 patients known to be alive (because they were subsequently admitted) was linked with(More)
OBJECTIVE To determine the frequency and interhospital variation of bilirubin testing and identified hyperbilirubinemia in a large health maintenance organization. DESIGN Retrospective cohort study. SETTING Eleven Northern California Kaiser Permanente hospitals. SUBJECTS A total of 51,387 infants born in 1995-1996 at >/= 36 weeks' gestation and >/=(More)
OBJECTIVE To investigate biological and health services predictors of extreme neonatal hyperbilirubinemia in a health maintenance organization. DESIGN Nested case-control study. SETTING Eleven Northern California Kaiser Permanente hospitals. SUBJECTS The cohort consisted of 51,387 newborns born at 36 weeks or later weighing 2000 g or more. Cases were(More)
OBJECTIVE To investigate the association between neonatal hyperbilirubinemia and autism spectrum disorders (ASD). METHODS We conducted a large case-control study nested within the cohort of singleton term infants born between 1995 and 1998 at a northern California Kaiser Permanente hospital. Case subjects (n = 338) were children with an ASD diagnosis(More)
On February 2, 2004, the Food and Drug Administration organized a joint meeting of the Neuro-Psychopharmacologic Advisory Committee and Pediatric Subcommittee of the Anti-Infective Drugs Advisory Committee to examine the occurrence of suicidality in clinical trials that investigate the use of the newer antidepressant drugs in pediatric patients. Committee(More)
U-shaped association between the level of blood A cholesterol and subsequent mortality has been reported in many studies over the past two decades.1-3 The right-hand limb of the U is the well known higher risk of death from coronary heart disease (CHD) at higher levels of blood cholesterol; this positive association, shown in clinical trials to be causal(More)
OBJECTIVE To determine the predictors and results of urine testing of young febrile infants seen in office settings. DESIGN Prospective cohort study. SETTING Offices of 573 pediatric practitioners from 219 practices in the American Academy of Pediatrics Pediatric Research in Office Settings' research network. SUBJECTS A total of 3066 infants 3 months(More)