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The ability to assay a variety of metals by noninvasive methods has applications in both biomedical and environmental research. Green fluorescent protein (GFP) is a protein isolated from coelenterates that exhibits spontaneous fluorescence. GFP does not require any exogenous cofactors for fluorescence, and can be easily appended to other proteins at the DNA… (More)
We describe two boys with cytogenetically identical interstitial deletions in the q42.11-q42.13 region of the long arm of chromosome 1 detected by high-resolution G-banding analysis. These children share some phenotypic features but also exhibit distinct morphologic differences. We further characterized the deletions using a new technical… (More)
OBJECTIVE To describe a considerably advanced method of array painting, which allows the rapid, ultra-high resolution mapping of translocation breakpoints such that rearrangement junction fragments can be amplified directly and sequenced. METHOD Ultra-high resolution array painting involves the hybridisation of probes generated by the amplification of… (More)
We describe the semilattice of ordered compactifications of X×Y smaller than β o X×β o Y where X and Y are certain totally ordered topological spaces, and where β o Z denotes the Stone– ˇ Cech ordered-or Nachbin-compactification of Z. These basic cases are used to illustrate techniques for describing the semilattice of ordered compactifications of X×Y… (More)
Order-theoretically connected posers are introduced and applied to create the notion of T-connectivity in ordered topological spaces. As special cases T-connectivity contains classical connectivity, order-connectivity, and link-connectivity.