Furfural and 5-hydroxymethylfurfural (HMF), released during thermo-chemical degradation of lignocellulosic biomass, inhibit microbial fermentation of sugars to biofuels. One approach to circumvent this roadblock is through microbial degradation of furaldehydes in biomass hydrolysates. Since these furaldehydes are the most common and abundant volatile… (More)
BACKGROUND Genetic variations represented as single nucleotide polymorphisms (SNPs) vary across the world population. This genetic polymorphism (such as SNPs) plays an important role in pharmacogenomics. SNPs that affects cellular metabolism, by altering the enzyme activity, have an important role in therapeutic outcome. Allele frequencies in number of… (More)
Here, we report the draft genome sequence of Burkholderia pseudomallei CM_Manipal, the causative agent of melioidosis isolated from a diabetic patient in Manipal, southern India. The draft genome consists of 107 contigs and is 7,209,157 bp long. A total of 5,600 coding sequences (CDSs), 60 tRNAs, 12 rRNAs, and one noncoding RNA (ncRNA) were predicted from… (More)
Eighty four different fungal endophytes isolated from sea grasses (5), marine algae (36) and leaves or barks of forest trees (43) were grown in vitro and the secondary metabolites secreted by them were harvested by immobilizing them on XAD beads. These metabolites were eluted with methanol and screened using SYBR Green I assay for their antiplasmodial… (More)
Staphylococcus aureus is a major pathogen associated with diabetic foot ulcer infections. To gain insight into their pathogenicity and virulence potential, we report draft genome sequences of four strains of Staphylococcus aureus, isolated from diabetic foot ulcers, showing profiles with various degrees of resistance to common antibiotics.