Thj Niedermeyer

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The normal sexual dimorphism in murine hepatic hexobarbital metabolism (i.e. females greater than males) was found to be absent in senescent animals. Hexobarbital metabolism, expressed as microsomal activity of hexobarbital hydroxylase and hexobarbital-induced sleep time, in senescent male mice was similar to that in females, but significantly greater than(More)
Serum levels of dehydroepiandrosterone, androstenedione, testosterone, and dihydrotestosterone were measured in intact, orchiectomized and orchiectomized-androgen-treated CD-1 mice. Although dehydroepiandrosterone was not detectable in the serum of old mice, approximately half of the very substantial serum concentration of this hormone found in the mature(More)
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