Thirunavukkarasu Bharani

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BACKGROUND Microbial resource orchid is a collection of Gram-positive and Gram-negative clinical isolates sourced from different hospitals and diagnostic laboratories in India. We determined the antibiotic susceptibility of a set of Gram-negative Enterobacteriaceae and non-fermenter clinical isolates from microbial resource orchid, collected during the(More)
A set of 12 novel hydroxamate compounds (NHCs), structurally designed as inhibitors of histone deacetylase (HDAC) enzyme, were synthesized at our facility. These were adamantane derivatives with N-hydroxyacetamide as pharmacophore, and each of these compounds was tested for potentiating activity on fluconazole. The concentration of fluconazole which(More)
A series of new Thienyl acrylate compounds were synthesized via Baylis-Hillman reaction and tested to demonstrate in vitro antimicrobial activity. Some of these compounds exhibited a very good activity against Gram positive strains. The structure of these newly synthesized compounds were conformed by 1 H NMR, IR, Mass and Elemental analysis, some of them(More)
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