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  • Md Hasan Zaki, Kelli Lynn Boyd, Peter Vogel, Michael B. Kastan, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
  • Medicine, Biology
  • Immunity
  • 2010 (First Publication: 26 March 2010)
  • Decreased expression of the Nlrp3 protein is associated with susceptibility to Crohn's disease. However, the role of Nlrp3 in colitis has not been characterized. Nlrp3 interacts with the adaptorExpand
  • Jénnifer Martínez, R K Subbarao Malireddi, +10 authors Douglas R. Green
  • Biology, Medicine
  • Nature Cell Biology
  • 2015 (First Publication: 1 July 2015)
  • LC3-associated phagocytosis (LAP) is a process wherein elements of autophagy conjugate LC3 to phagosomal membranes. We characterize the molecular requirements for LAP, and identify Rubicon as beingExpand
  • Thirumala-Devi Kanneganti, Mathilde Body-Malapel, +8 authors Gabriel Núñez
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2006 (First Publication: 1 December 2006)
  • Viral infection induces the production of interleukin (IL)-1β and IL-18 in macrophages through the activation of caspase-1, but the mechanism by which host cells sense viruses to induce caspase-1Expand
  • Jorunn I. B. Bos, Thirumala-Devi Kanneganti, +6 authors Sophien Kamoun
  • Medicine, Biology
  • The Plant journal : for cell and molecular…
  • 2006 (First Publication: 1 October 2006)
  • The RXLR cytoplasmic effector AVR3a of Phytophthora infestans confers avirulence on potato plants carrying the R3a gene. Two alleles of Avr3a encode secreted proteins that differ in only three aminoExpand