• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
  • Marco Mongillo, Theresa McSorley, +9 authors Manuela Zaccolo
  • Biology, Medicine
  • Circulation research
  • 2004 (First Publication: 27 May 2004)
  • Cardiac myocytes have provided a key paradigm for the concept of the compartmentalized cAMP generation sensed by AKAP-anchored PKA. Phosphodiesterases (PDEs) provide the sole route for degrading cAMPContinue Reading
  • Simon J. Mackenzie, George S Baillie, +7 authors Miles D Houslay
  • Medicine, Chemistry
  • British journal of pharmacology
  • 2002 (First Publication: 1 June 2002)
  • 1. Challenge of COS1 cells with the adenylyl cyclase activator forskolin led to the activation of recombinant PDE4A8, PDE4B1, PDE4C2 and PDE4D5 cAMP-specific phosphodiesterase long isoforms. 2.Continue Reading
  • Angela McCahill, Theresa McSorley, +8 authors Miles D Houslay
  • Biology, Medicine
  • Cellular signalling
  • 2005 (First Publication: 1 September 2005)
  • We employ a novel, dominant negative approach to identify a key role for certain tethered cyclic AMP specific phosphodiesterase-4 (PDE4) isoforms in regulating cyclic AMP dependent protein kinase AContinue Reading
  • Jens Gruber, Wei Cun See Too, Mun Teng Wong, Arnon Lavie, Theresa McSorley, Manfred Konrad
  • Biology, Medicine
  • The FEBS journal
  • 2012 (First Publication: 1 June 2012)
  • The enzyme choline kinase (CK), which catalyzes the phosphorylation of choline to phosphorylcholine in the presence of ATP, has an essential role in the biosynthesis of phosphatidylcholine, the majorContinue Reading
  • Graeme B. Bolger, Angela McCahill, +4 authors Miles D Houslay
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2003 (First Publication: 5 December 2003)
  • Isoproterenol challenge of Hek-B2 cells causes a transient recruitment of the endogenous PDE4D isoforms found in these cells, namely PDE4D3 and PDE4D5, to the membrane fraction. PDE4D5 providesContinue Reading