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  • Theodore P. Broten, Joseph L. Romson, David A. Fullerton, Donna M van Winkle, Eric O. Feigl
  • Medicine, Chemistry
  • Circulation research
  • 1991 (First Publication: 1 February 1991)
  • A two-part experiment was designed to test the hypothesis that myocardial oxygen and carbon dioxide tensions, as measured by coronary venous oxygen and carbon dioxide tensions, determine coronaryContinue Reading
  • James C Barrow, Philippe G. Nantermet, +20 authors Carlos Forray
  • Medicine
  • Journal of medicinal chemistry
  • 2000
  • alpha(1) Adrenergic receptors mediate both vascular and lower urinary tract tone, and alpha(1) receptor antagonists such as terazosin (1b) are used to treat both hypertension and benign prostaticContinue Reading
  • B. A. Johns, Theodore P. Broten, Maria T. Stranieri, Marie A. Holahan, Jacquelynn J. Cook
  • Chemistry, Medicine
  • Journal of chromatography. B, Biomedical sciences…
  • 2001 (First Publication: 1 August 2001)
  • A simple method for creatinine determination was developed using high-performance liquid chromatography (HPLC) to more accurately monitor serum creatinine levels in experimental animal models whenContinue Reading
  • Dhanapalan Nagarathnam, S W Miao, +22 authors Charles Harrell
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1999 (First Publication: 1 November 1999)
  • Dihydropyrimidinones such as compound 12 exhibited high binding affinity and subtype selectivity for the cloned human alpha(1a) receptor. Systematic modifications of 12 led to identification ofContinue Reading