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To investigate the role of phosphatases in synaptic plasticity using genetic approaches, we generated transgenic mice that overexpress a truncated form of calcineurin under the control of the… (More)
- Isabelle M Mansuy, Danny G. Winder, +4 authors Eric R Kandel
- Neuron
- 1998
To obtain rapidly inducible and reversible expression of transgenes in the forebrain of the mouse, we have combined the reverse tetracycline-controlled transactivator (rtTA) system with the… (More)
- Peter T. Ohara, Alberto Granato, Theodore M. Moallem, Bai-ren Wang, Yves Tillet, Luc Jasmin
- Journal of neurocytology
- 2003
Increasing evidence shows that the rostral agranular insular cortex (RAIC) is important in the modulation of nociception in humans and rats and that dopamine and GABA appear to be key… (More)
This study examines the contribution of central corticotropin-releasing factor (CRF) to pain behavior. CRF is the principal modulator of the hypothalamo-pituitary-adrenal (HPA) axis, in addition to… (More)
- Luc Jasmin, Gabriella Janni, Theodore M. Moallem, Douglas A. Lappi, Peter T. Ohara
- The Journal of neuroscience : the official…
- 2000
Remyelination of the CNS is necessary to restore neural function in a number of demyelinating conditions. Schwann cells, the myelinating cells of the periphery, are candidates for this purpose… (More)
- Vladimir Sobolev, Theodore M. Moallem, Rebecca C. Wade, Gert Vriend, Marvin Edelman
- Proteins
- 1997
Seven docking predictions were made with the LIGIN program. In six cases the location of the binding pocket was identified correctly by systematically docking everywhere within the protein structure.… (More)
Goals and Significance The long-term goal of this research is to develop tactual aids for persons who are profoundly deaf or deaf-blind to serve as a substitute for hearing in the reception of speech… (More)
The long-term goal of this research is to develop tactual aids for persons who are profoundly deaf or deaf-blind to serve as a substitute for hearing in the reception of speech and environmental… (More)
This thesis builds on previous efforts to develop tactile speech-reception aids for the hearingimpaired. Whereas conventional hearing aids mainly amplify acoustic signals, tactile speech aids convert… (More)
The long-term goal of this research is to develop tactual aids for persons who are profoundly deaf or deaf-blind to serve as a substitute for hearing in the reception of speech and environmental… (More)