Aquaporin-2: COOH terminus is necessary but not sufficient for routing to the apical membrane.Peter Meinardus T. Deen, Bas W. M. van Balkom, +6 authors Michael J. CaplanAmerican journal of physiology. Renal physiology2002Renal regulation of mammalian water homeostasis is mediated by the aquaporin-1 (AQP1) water channel, which is expressed in the apical and basolateral membranes of proximal tubules and descending… (More)